Circulate chart getting participant choice. Contained in this investigation, i mentioned the latest urinary Na/K ratio and you will BP from inside the several,890 people (84% out-of members were regarding 2017) for two ages. In the long run, several,877 professionals were reviewed
Na/K ratio
Tome Area asked people to collect their pee trials just after waking was. Brand new urinary Na/K proportion try measured having fun with a great urinary Na/K ratio-calculating unit named HEU-001F (OMRON Health care Co., Ltd., Kyoto, Japan) (Additional Fig. 1). The fresh display screen instantly ideas urinary Na/K proportion measurements. A community nursing assistant measured the fresh new Na/K ratio throughout the spot pee types of the players using the machine, recorded the significance, and you can provided quick views for the users about your measured worthy of and additionally explanatory question regarding dating within urinary Na/K proportion and you can BP (Supplementary Fig. 2). Tome Area work fitness checkups for the each area yearly regarding May to help you Sep. For this reason, participants might have the urinary Na/K proportion mentioned at the same time both in 2017 and you can 2018.
Other specifications
Details about almost every other specifications was extracted from the checkup studies regarding Tome Town. One another lbs and the entire body height had been counted in wellness checkup. Bmi was determined because the weight (kg)/level dos (meters dos ). BP was counted twice by an experienced societal health nurse. Just like the health checkup analysis available with Tome Town merely included the lower BP dimension of the two BP dimensions opinions, we are able to only is that it really worth in our study. Blood pressure are recognized as systolic BP (SBP) ? 140 mmHg or diastolic BP (DBP) ? ninety mmHg and you may/or perhaps the usage of antihypertensive medication. Information regarding liquor consumption are acquired from the a questionnaire. We calculated the fresh alcoholic drinks consumption a week as follows: i increased the latest regularity regarding alcoholic beverages (day-after-day = seven, possibly = step three.5, without habitual taking = 0) and you will quantity of liquor used an individual https://datingranking.net/tr/faceflow-inceleme/ celebration (0–1 drink = 0.5, 1–2 drinks = 1.5, 2–3 products = 2.5, and you may 3 drinks or more = 3) and split up the item by the 7. You to definitely drink within the The japanese represents 23 grams away from ethanol. Analysis on the means to access all forms of diabetes cures and treatment for cardio state was basically self-advertised about health checkup studies.
Regarding information on the effective use of diabetes treatment, players picked you to option from the after the responses: (a) a history of diabetic issues, (b) below way to all forms of diabetes mellitus, otherwise (c) access to all forms of diabetes treatment. Those who replied (c) was basically categorized since “users out-of diabetes therapy,” while people who replied with (a) or (b) or not appropriate have been classified since the “other people.” Pertaining to information regarding the procedure to own heart disease, users selected one solution regarding adopting the solutions: (a) enjoys a history of cardiovascular disease otherwise (b) undergoing treatment to possess heart problems. Individuals who replied (b) was in fact categorized since “being treated to possess cardiovascular illnesses,” whereas those who answered which have (a) or otherwise not appropriate was classified given that “anybody else.”
Statistical analysis
To compare the difference between participants who attended health checkups both in 2017 and 2018 and those who attended health checkups only in 2017, we used the t-test for continuous variables and the chi-square test for categorical variables. For each year, we compared the baseline characteristics according to the urinary Na/K ratio level. Moreover, we analyzed the relationship between the urinary Na/K ratio and hypertension adjusted for age, sex, BMI, alcohol intake, use of diabetes medication, and treatment for heart disease. For longitudinal data, we assessed the relationship between change in urinary Na/K ratio and BP change using multiple regression analyses adjusted for age, sex, BMI change, and alcohol intake. In both cross-sectional and longitudinal analyses, we stratified the data according to the use of antihypertensive medication. We further added SBP or DBP in 2017 as a covariate. Furthermore, we analyzed the BP difference according to the urinary Na/K ratio quartile in 2017. To examine the effect of BP due to temperature, we acquired past temperature data from the Japan Meteorological Agency in 2017 and 2018 . We considered P < 0.05 as statistically significant.